Found 77 Enz. Inhib. hit(s) with Target = 'Thyrotropin receptor' 
Affinity DataIC50: 8nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 10nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 11nMAssay Description:Allosteric antagonist activity at human TSHR expressed in CHO cells assessed as inhibition of bTSH-induced cAMP production incubated for 2 hrs by lum...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 12nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 18nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 21nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 21nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 22nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as inhibition of M22-induced cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 30nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 38nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 39nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 47nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 48nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 48nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 68nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 69nMAssay Description:Antagonist activity at human TSHR in HEK293 cells assessed as inhibition of bTSH-induced cAMP production incubated for 2 hrs by Eu-cAMP tracer based ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 76nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 83nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 84nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 88nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 91nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 97nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
